Telomerase Gene Therapy Extends Mouse Lifespan by 24%

mouse-pushing-wheel

Inducing cells to express telomerase, the enzyme which is supposed to slow down the metabolic clock, has enabled researchers boost the lifespan of mouse by 24% with a single treatment.

Read more @ SciTechDaily

4 Responses to “Telomerase Gene Therapy Extends Mouse Lifespan by 24%”


  1. 1 bluewoodtree December 1, 2012 at 17:00

    Sure, but what about increased cancer risk? I mean, you are messing up with apoptosis regulation…

    • 2 range December 2, 2012 at 03:57

      The results come from a cancer research group, and at least in mouse models, there seemed to be no increased risk of cancer, but how this will translate into humans is another question.

      • 3 bluewoodtree December 2, 2012 at 06:45

        I was just thinking about when they discovered years ago that suppressed telomerase activity decreases cancer, thus it sounds a little bit controversial to me. I mean, if the cell lives longer by counter-acting the telomere-shortening it will also accumulate all sorts of mutations, which will eventually lead to cancer. Maybe this is not such a big problem in mice, because their average life span is so much shorter than for humans.

  2. 4 range December 2, 2012 at 14:19

    That’s probably one of the reasons why telomerase-based therapies were abandoned in the past.


Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s




subscribe to feed

About

ranjitwithkinginbehand.jpgI'm Range, your host. On the menu, photos, art, stories, entertainment and reviews. Links, maths, education and social issues. I'm in Quebec (Canada) or Taiwan (R.O.C.). Follow me on Twitter.

click to subscribe to The Memoirs & receive updates by email.

Join 1,458 other followers

@djrange: my tweets

channels

archives

del.icio.us

translate the memoirs

copyright notice & disclaimer

Please view the full disclaimer and copyright notice here
free web tracker

© 2006-2012 Range all rights reserved


Follow

Get every new post delivered to your Inbox.

Join 1,458 other followers

%d bloggers like this: