Fear of Immune Response to Induced Stem Cells Overstated

Induced pluripotent stem cells

Scientists report that induced pluripotent stem cells (iPS) have a similar immune response in mice as embryonic stem cells (ES).

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Steps That Enable Human Stem Cells to Develop Into Egg Cells

Human egg cell in the womb

The exact causes of infertility, which can affect around 10% of couples, are often unknown. In some cases, it may be a result of the body’s inability to produce viable gametes. A new study of the development of germ cells from humans could help scientists learn how to create them in the laboratory.

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Stem Cells Help Restore a Man’s Vision

Doctors at Toronto Western Hospital preform a stem cell transplant to help a patient regain their sight. Credit: CTV News

Taylor Binns began slowly going blind because of complications with his contact lenses. However, an innovative treatment using stem cells has allowed him to regain his sight.

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Paralyzed Dog Walks Again Thanks to Stem Cell Transplant


Researchers have used pet dogs, with real injuries, to test a treatment that involved transplanting cells from the lining of the nose and injecting them into the spine in an attempt to bridge the damage in their spinal column.

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Hisashi Moriguchi’s Stem-Cell Transplant Claims Refuted

Immune cells infiltrate tissue grown from induced pluripotent stem cells. Photograph: Yang Xu/UC San Diego

Just days after Kyoto University biologist Shinya Yamanaka won the Nobel Prize for his discovery of induced pluripotent stem cells (iPS), Hisashi Moriguchi, a visiting researcher at the University of Tokyo, claimed to have modified that technology to treat a person with terminal heart failure. Eight months after the treatment, the patient was reported to be healthy.

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Medicine Nobel Prize Awarded to Researchers for Reprogramming Mature Cells to a Pluripotent State

John Gurdon (left) and Shinya Yamanaka showed how to reprogram cells into their embryonic states.

The discovery that mature, adult cells can be reprogrammed back to an embryonic-like state has won this year’s Nobel Prize in Physiology or Medicine. It was awarded to two pioneers of stem-cell research, John Gurdon and Shinya Yamanaka.

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Lab-Made Mouse Oocytes Produce Fertile and Viable Offspring


Japanese scientists have been able to coax mouse stem cells into becoming viable eggs that were able to produce healthy offspring. This will provide a powerful tool to study the basic elements of mammalian development and infertility.

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Human Embryonic Stem Cells Restore Partial Hearing in Gerbils

Human stem cells differentiated into auditory neurons.

There are more than 275 million people that have moderate to profound hearing loss, and many are caused by a breach in the connection between the inner ear and the brain. Researchers have discovered that a key component in repairing the auditory nerve is human embryonic stem cells.

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For the First Time, Cancer Stem Cells Tracked, May Inform Treatment Strategies

For the first time, researchers can trace cell lineage within a growing tumor. In this skin tumor, the cells labeled red all arose from a single stem cell.

Until now, cancer researchers haven’t been able to track what errant cancer cells have been doing in patient’s bodies, ie forming tumors. Three different groups studying tumors in mice have accomplished this. Their results support ideas that a small subset of cells drive tumor growth and that curing cancer would require eliminating these rogue cells.

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Human Cardiac Cells Derived from Stem Cells Could Repair Damaged Hearts

Cardiomyocytes-humanContrary to the skin and liver, damaged hearts rarely heal themselves but there is new research that might raise hope for cell therapies. It’s been recently shown that heart muscle cells differentiated from human embryonic stem cell could be reintegrated into an existing heart muscle.

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